Linked Life Data

15161048

Source:http://linkedlifedata.com/resource/pubmed/id/15161048

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2B
pubmed:dateCreated
2004-5-26
pubmed:abstractText
Cancer-related molecular targets of green tea polyphenols, such as (-)-epigallocatechin-3-gallate [(-)-EGCG], remain unknown. We previously showed that (-)-EGCG is a potent and specific inhibitor of the proteasomal chymotrypsin-like activity in vitro and in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
943-54
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15161048-Amides, pubmed-meshheading:15161048-Antineoplastic Agents, Phytogenic, pubmed-meshheading:15161048-Carrier Proteins, pubmed-meshheading:15161048-Catechin, pubmed-meshheading:15161048-Cell Cycle Proteins, pubmed-meshheading:15161048-Cell Line, Transformed, pubmed-meshheading:15161048-Cysteine Endopeptidases, pubmed-meshheading:15161048-Humans, pubmed-meshheading:15161048-Inhibitory Concentration 50, pubmed-meshheading:15161048-Jurkat Cells, pubmed-meshheading:15161048-Male, pubmed-meshheading:15161048-Multienzyme Complexes, pubmed-meshheading:15161048-Neoplastic Stem Cells, pubmed-meshheading:15161048-Prostatic Neoplasms, pubmed-meshheading:15161048-Proteasome Endopeptidase Complex, pubmed-meshheading:15161048-Structure-Activity Relationship, pubmed-meshheading:15161048-Tea
pubmed:articleTitle
Structure-activity relationships of synthetic analogs of (-)-epigallocatechin-3-gallate as proteasome inhibitors.
pubmed:affiliation
Drug Discovery Program, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida, Tampa, Florida 33612, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't