Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2B
pubmed:dateCreated
2004-5-26
pubmed:abstractText
The efficacy of FK228, a histone deacetylase inhibitor that is currently under early clinical trials for cancer therapy, against N-butyl-N-(4-hydroxybutyl)- nitrosamine (BBN) -induced mouse urinary bladder carcinogenesis was examined.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antibiotics, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Butylhydroxybutylnitrosamine, http://linkedlifedata.com/resource/pubmed/chemical/Carcinogens, http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1a protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/Cyclins, http://linkedlifedata.com/resource/pubmed/chemical/Depsipeptides, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Peptides, Cyclic, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53, http://linkedlifedata.com/resource/pubmed/chemical/romidepsin
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
785-90
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:15161027-Animals, pubmed-meshheading:15161027-Antibiotics, Antineoplastic, pubmed-meshheading:15161027-Body Weight, pubmed-meshheading:15161027-Butylhydroxybutylnitrosamine, pubmed-meshheading:15161027-Carcinogens, pubmed-meshheading:15161027-Cyclin-Dependent Kinase Inhibitor p21, pubmed-meshheading:15161027-Cyclins, pubmed-meshheading:15161027-Depsipeptides, pubmed-meshheading:15161027-Eating, pubmed-meshheading:15161027-Enzyme Inhibitors, pubmed-meshheading:15161027-Histone Deacetylase Inhibitors, pubmed-meshheading:15161027-Male, pubmed-meshheading:15161027-Mice, pubmed-meshheading:15161027-Organ Size, pubmed-meshheading:15161027-Peptides, Cyclic, pubmed-meshheading:15161027-Precancerous Conditions, pubmed-meshheading:15161027-Tumor Suppressor Protein p53, pubmed-meshheading:15161027-Urinary Bladder Neoplasms
pubmed:articleTitle
Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in p53+/- and p53+/+ mice.
pubmed:affiliation
Department of Pathology, Osaka City University Medical School, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't