rdf:type |
|
lifeskim:mentions |
umls-concept:C0015677,
umls-concept:C0017337,
umls-concept:C0040005,
umls-concept:C0205419,
umls-concept:C0232478,
umls-concept:C0332307,
umls-concept:C0376674,
umls-concept:C0681850,
umls-concept:C0851827,
umls-concept:C1173118,
umls-concept:C1333525,
umls-concept:C1550501,
umls-concept:C1553189,
umls-concept:C1701901,
umls-concept:C1706203,
umls-concept:C1706412,
umls-concept:C2349001,
umls-concept:C2697811
|
pubmed:issue |
6
|
pubmed:dateCreated |
2004-5-25
|
pubmed:abstractText |
The alanine-for-threonine substitution at codon 54 (A54T polymorphism) in the fatty acid-binding protein 2 gene (FABP2) has been associated with hypertriglyceridemia and insulin resistance. Obese and diabetic T54 carriers have greater postprandial lipemia than do A54 homozygotes. The T54 protein isoform is also associated with increased triacylglycerol secretion in vitro.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/FABP2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FABP7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acid-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0002-9165
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
79
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1110-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15159243-Adult,
pubmed-meshheading:15159243-Blood Glucose,
pubmed-meshheading:15159243-Carrier Proteins,
pubmed-meshheading:15159243-Cholesterol,
pubmed-meshheading:15159243-Cross-Over Studies,
pubmed-meshheading:15159243-Dietary Fats,
pubmed-meshheading:15159243-Fatty Acid-Binding Proteins,
pubmed-meshheading:15159243-Female,
pubmed-meshheading:15159243-Genotype,
pubmed-meshheading:15159243-Humans,
pubmed-meshheading:15159243-Lipids,
pubmed-meshheading:15159243-Male,
pubmed-meshheading:15159243-Postprandial Period,
pubmed-meshheading:15159243-Tumor Suppressor Proteins
|
pubmed:year |
2004
|
pubmed:articleTitle |
Postprandial lipemia in subjects with the threonine 54 variant of the fatty acid-binding protein 2 gene is dependent on the type of fat ingested.
|
pubmed:affiliation |
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|