Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2004-5-25
pubmed:abstractText
The existence of sphingolipid- and cholesterol-rich membrane microdomains called "lipid rafts", as well as their role in lymphocyte biology, has been widely debated during the last few years. Plasma membrane microdomains seem to be primarily involved in initiation and propagation of the signal transduction cascade associated with lymphocyte activation. In this review, we discuss the recent literature suggesting that, during lymphocyte activation and chemotaxis, lipid rafts act as platforms to compartmentalise signalling and facilitate specific protein-protein interactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1286-4579
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
686-92
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Lipid rafts in lymphocyte activation.
pubmed:affiliation
Department of Biomedical Sciences, University of Padova, Viale Giuseppe Colombo 3, I-35121, Italy. paola.pizzo@unipd.it
pubmed:publicationType
Journal Article, Review