Source:http://linkedlifedata.com/resource/pubmed/id/15158756
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-3
|
| pubmed:dateCreated |
2004-5-25
|
| pubmed:abstractText |
Acyl-CoA:cholesterol acyltransferase (ACAT) plays important roles in cellular cholesterol homeostasis. Two isoforms of ACAT have been reported (ACAT-1 and ACAT-2). ACAT inhibitors cannot only prevent atherosclerosis formation, but may also induce its regression in animals. In humans, an ACAT inhibitor was shown to have a lipid-lowering effect. The present study was carried out to clarify the relationship between ACAT-1 gene variants and hyperlipidemia.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0006-3002
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
1682
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
56-62
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:15158756-Apolipoprotein A-I,
pubmed-meshheading:15158756-Cholesterol, HDL,
pubmed-meshheading:15158756-Exons,
pubmed-meshheading:15158756-Female,
pubmed-meshheading:15158756-Humans,
pubmed-meshheading:15158756-Hyperlipidemias,
pubmed-meshheading:15158756-Male,
pubmed-meshheading:15158756-Middle Aged,
pubmed-meshheading:15158756-Point Mutation,
pubmed-meshheading:15158756-Polymorphism, Single Nucleotide,
pubmed-meshheading:15158756-Sterol O-Acyltransferase
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G-->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects.
|
| pubmed:affiliation |
Department of Pediatrics, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0125, Japan. tohta@med.u-ryukyu.ac.jp
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|