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rdf:type |
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lifeskim:mentions |
umls-concept:C0003864,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0023810,
umls-concept:C0024429,
umls-concept:C0026809,
umls-concept:C0205263,
umls-concept:C0312359,
umls-concept:C0443923,
umls-concept:C0678226,
umls-concept:C1261381,
umls-concept:C1334507,
umls-concept:C1442161
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pubmed:issue |
5
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pubmed:dateCreated |
2004-5-25
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pubmed:abstractText |
Previous studies have demonstrated that neutralization of macrophage migration inhibitory factor (MIF) by anti-MIF antibody decreases joint destruction in the collagen-induced arthritis model. The present study was undertaken to investigate whether selective deletion of MIF inhibits inflammation and joint destruction of the anti-type II collagen antibody (anti-CII Ab)/lipopolysaccharide (LPS)-induced arthritis in mice, in order to determine the role of this cytokine in inflammatory arthritis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Collagenases,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcl2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Intramolecular Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Macrophage Migration-Inhibitory...,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 13,
http://linkedlifedata.com/resource/pubmed/chemical/Mif protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp13 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1043-4666
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 Elsevier Ltd.
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pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-94
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15157895-Animals,
pubmed-meshheading:15157895-Antibodies, Monoclonal,
pubmed-meshheading:15157895-Arthritis, Rheumatoid,
pubmed-meshheading:15157895-Chemokine CXCL2,
pubmed-meshheading:15157895-Chemokines,
pubmed-meshheading:15157895-Collagen Type II,
pubmed-meshheading:15157895-Collagenases,
pubmed-meshheading:15157895-Intramolecular Oxidoreductases,
pubmed-meshheading:15157895-Lipopolysaccharides,
pubmed-meshheading:15157895-Macrophage Migration-Inhibitory Factors,
pubmed-meshheading:15157895-Matrix Metalloproteinase 13,
pubmed-meshheading:15157895-Mice,
pubmed-meshheading:15157895-RNA, Messenger,
pubmed-meshheading:15157895-Synovial Membrane,
pubmed-meshheading:15157895-Time Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Inhibition of joint inflammation and destruction induced by anti-type II collagen antibody/lipopolysaccharide (LPS)-induced arthritis in mice due to deletion of macrophage migration inhibitory factor (MIF).
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pubmed:affiliation |
Department of Sports Medicine and Joint Reconstruction Surgery, Hokkaido University School of Medicine, Kita-ku Kita-15 Nishi-7, Sapporo 060-8638, Japan.
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pubmed:publicationType |
Journal Article
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