To determine the pharmacokinetics of adaptively dosed carboplatin when administered in combination with the bradykinin agonist, lobradimil (RMP-7, Cereport), to pediatric patients with brain tumors.
Neuro-Oncology Branch and Pediatric Oncology Branch, National Cancer Institute, Bloch Building, #82, 9030 Old Georgetown Road, Bethesda, MD 20892-8200, USA. warrenk@mail.nih.gov