Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2004-10-19
pubmed:abstractText
An unexpected image made by an invisible beam precipitated the discovery of X-rays in the waning days of the 19th century. The usefulness and dangers of this new discovery soon became clear, emphasizing the importance of DNA damage recognition and repair after exposure to ionizing radiation (IR). One hundred years later, new images of the immediate effects of ionizing radiation have once again ignited excitement among investigators. The combination of advanced imaging techniques with new reagents targeting molecular components of the cellular DNA damage response have enabled visualization of sites of DNA damage, resulting in fresh insights into the immediate cell biological effects of IR. This review will review these advances, highlighting recent progress as well as critical questions that remain unanswered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1538-4047
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
602-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Pictures, progress, and perplexities: the immediate cell biological effects of ionizing radiation.
pubmed:affiliation
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
pubmed:publicationType
Journal Article, Review, Historical Article, Portraits