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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-5-19
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pubmed:abstractText |
The synthesis of a novel series of 1,7-annulated indolocarbazoles 2 and 16 is described. These compounds were found to be potent cyclin dependent kinase inhibitors with good antiproliferative activity against two human carcinoma cell lines. These inhibitors also arrested tumor cells at the G1 phase and inhibited pRb phosphorylation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:Al-AwarRima SRS,
pubmed-author:BrooksHarold BHB,
pubmed-author:ChanHo-KitHK,
pubmed-author:ConnerScott ESE,
pubmed-author:ConsidineEileen LEL,
pubmed-author:DempseyJack AJA,
pubmed-author:EnglerThomas ATA,
pubmed-author:LytleMichelle LML,
pubmed-author:OggCatherine ACA,
pubmed-author:PatelBharvin RBR,
pubmed-author:SchultzRichard MRM,
pubmed-author:ShihChuanC,
pubmed-author:SpencerCharles DCD,
pubmed-author:VasudevanVasuV,
pubmed-author:WatkinsScott ASA,
pubmed-author:ZhouXunX,
pubmed-author:ZhuGuoxinG
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3057-61
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
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pubmed:year |
2004
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pubmed:articleTitle |
Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.
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pubmed:affiliation |
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA. zhu_guoxin@lilly.com
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pubmed:publicationType |
Journal Article
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