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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-5-19
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pubmed:abstractText |
Relaxin (RLX) is a peptide hormone that stimulates the breakdown of collagen in preparation for parturition and when administered to various models of induced fibrosis. However, its significance in the aging kidney is yet to be established. In this study, we compared structural and functional changes in the kidney of aging relaxin-1 (RLX-/-) deficient mice and normal (RLX+/+) mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Peptide,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Relaxin,
http://linkedlifedata.com/resource/pubmed/chemical/relaxin receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2054-64
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15149318-Aging,
pubmed-meshheading:15149318-Animals,
pubmed-meshheading:15149318-Collagen,
pubmed-meshheading:15149318-Female,
pubmed-meshheading:15149318-Fibrosis,
pubmed-meshheading:15149318-Gene Expression,
pubmed-meshheading:15149318-Humans,
pubmed-meshheading:15149318-Kidney,
pubmed-meshheading:15149318-Male,
pubmed-meshheading:15149318-Mice,
pubmed-meshheading:15149318-Mice, Inbred C57BL,
pubmed-meshheading:15149318-Mice, Knockout,
pubmed-meshheading:15149318-Proteins,
pubmed-meshheading:15149318-RNA, Messenger,
pubmed-meshheading:15149318-Receptors, G-Protein-Coupled,
pubmed-meshheading:15149318-Receptors, Peptide,
pubmed-meshheading:15149318-Recombinant Proteins,
pubmed-meshheading:15149318-Relaxin
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pubmed:year |
2004
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pubmed:articleTitle |
Relaxin-1-deficient mice develop an age-related progression of renal fibrosis.
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pubmed:affiliation |
Howard Florey Institute of Experimental Physiology & Medicine, The University of Melbourne, Parkville, Victoria, Australia. c.samuel@hfi.unimelb.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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