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pubmed-article:15146525pubmed:abstractTextThe total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-supported reagents, catalysts, scavengers and catch-and-release techniques to avoid frequent aqueous work-up and chromatographic purification.lld:pubmed
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pubmed-article:15146525pubmed:authorpubmed-author:LeySteven VSVlld:pubmed
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pubmed-article:15146525pubmed:dateRevised2009-8-4lld:pubmed
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pubmed-article:15146525pubmed:articleTitleMulti-step application of immobilized reagents and scavengers: a total synthesis of epothilone C.lld:pubmed
pubmed-article:15146525pubmed:affiliationDepartment of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.lld:pubmed
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pubmed-article:15146525pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed