rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2004-5-17
|
pubmed:abstractText |
The total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-supported reagents, catalysts, scavengers and catch-and-release techniques to avoid frequent aqueous work-up and chromatographic purification.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0947-6539
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
17
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2529-47
|
pubmed:dateRevised |
2009-8-4
|
pubmed:meshHeading |
|
pubmed:year |
2004
|
pubmed:articleTitle |
Multi-step application of immobilized reagents and scavengers: a total synthesis of epothilone C.
|
pubmed:affiliation |
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|