| pubmed-article:15145515 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C0007133 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C0040136 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C0812241 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C0205422 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C1979874 | lld:lifeskim |
| pubmed-article:15145515 | lifeskim:mentions | umls-concept:C1518029 | lld:lifeskim |
| pubmed-article:15145515 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15145515 | pubmed:dateCreated | 2004-5-17 | lld:pubmed |
| pubmed-article:15145515 | pubmed:abstractText | Point mutations of the BRAF gene have been recently described with high prevalence in papillary thyroid carcinomas. However, this molecular alteration has not been studied in radiation-induced thyroid tumors. We analyzed the prevalence of BRAF point mutations and RET/PTC rearrangements in 55 post-Chernobyl papillary carcinomas, compared with 82 sporadic papillary carcinomas. Radiation-induced tumors demonstrated a low prevalence (4%) of BRAF point mutations and high prevalence (58%) of RET/PTC rearrangements. Sporadic papillary carcinomas revealed a clearly distinct pattern, with 37% of tumors harboring BRAF mutations and 20% RET/PTC rearrangements. These results demonstrate a significant difference in the molecular genetic profile of sporadic and radiation-induced thyroid tumors. | lld:pubmed |
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| pubmed-article:15145515 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15145515 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15145515 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15145515 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15145515 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15145515 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15145515 | pubmed:issn | 0304-3835 | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:SalvatoreGiul... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:SantoroMassim... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:NikiforovYuri... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:FaginJames... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:NikiforovaMar... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:KnaufJeffrey... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:GandhiManojM | lld:pubmed |
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| pubmed-article:15145515 | pubmed:author | pubmed-author:JeremiahSteph... | lld:pubmed |
| pubmed-article:15145515 | pubmed:author | pubmed-author:BogdanovaTaty... | lld:pubmed |
| pubmed-article:15145515 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15145515 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:15145515 | pubmed:volume | 209 | lld:pubmed |
| pubmed-article:15145515 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15145515 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15145515 | pubmed:pagination | 1-6 | lld:pubmed |
| pubmed-article:15145515 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:15145515 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15145515 | pubmed:articleTitle | Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. | lld:pubmed |
| pubmed-article:15145515 | pubmed:affiliation | Department of Pathology and Laboratory Medicine, University of Cincinnati, 231 Albert Sabin Way, P.O. Box 670529, Cincinnati, OH 45267 0529, USA. yuri.nikiforov@uc.edu | lld:pubmed |
| pubmed-article:15145515 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15145515 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15145515 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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