rdf:type |
|
lifeskim:mentions |
umls-concept:C0005456,
umls-concept:C0017337,
umls-concept:C0020792,
umls-concept:C0036849,
umls-concept:C0205245,
umls-concept:C0237876,
umls-concept:C0936012,
umls-concept:C1149367,
umls-concept:C1514562,
umls-concept:C1516769,
umls-concept:C1880157
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pubmed:dateCreated |
2004-7-7
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pubmed:abstractText |
Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition motifs located upstream of the coding region of the regulated gene. The computational identification of such motifs is made easier by the fact that they often appear several times in the upstream region of the regulated genes, so that the number of occurrences of relevant motifs is often significantly larger than expected by pure chance.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-10698627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-10734201,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-10802651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-10869030,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-11533229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-11876822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12399584,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12421759,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12464632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12520026,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12748633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12756250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-12824373,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-1386897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-1869554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-8641288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-8879249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-9427394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-9719638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-9847176,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15137914-9920414
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1471-2105
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15137914-5' Flanking Region,
pubmed-meshheading:15137914-Base Composition,
pubmed-meshheading:15137914-Binding Sites,
pubmed-meshheading:15137914-Computational Biology,
pubmed-meshheading:15137914-Consensus Sequence,
pubmed-meshheading:15137914-DNA, Fungal,
pubmed-meshheading:15137914-Gene Expression Regulation, Fungal,
pubmed-meshheading:15137914-Genes, Fungal,
pubmed-meshheading:15137914-Saccharomyces cerevisiae,
pubmed-meshheading:15137914-Transcription Factors,
pubmed-meshheading:15137914-Transcription Initiation Site
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pubmed:year |
2004
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pubmed:articleTitle |
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrepresented upstream motifs.
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pubmed:affiliation |
Dipartimento di Fisica Teorica, Università di Torino, and INFN, sezione di Torino, Italy. cora@to.infn.it
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pubmed:publicationType |
Journal Article
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