|
rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-5-11
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pubmed:abstractText |
Mutations in the GATA-1 gene have been identified in patients with familial macrothrombocytopenia and Down's syndrome patients with a transient myeloproliferative disorder and/or acute megakaryoblastic leukemia. We screened this gene in 46 patients with essential thrombocythemia and identified only a common single nucleotide polymorphism that is unlikely to be of pathological significance.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
May
|
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pubmed:issn |
1592-8721
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pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
613-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15136229-Animals,
pubmed-meshheading:15136229-Female,
pubmed-meshheading:15136229-GATA1 Transcription Factor,
pubmed-meshheading:15136229-HL-60 Cells,
pubmed-meshheading:15136229-Humans,
pubmed-meshheading:15136229-Mice,
pubmed-meshheading:15136229-Mice, Knockout,
pubmed-meshheading:15136229-Polymerase Chain Reaction,
pubmed-meshheading:15136229-Polymorphism, Single Nucleotide,
pubmed-meshheading:15136229-Thrombocythemia, Essential
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|
pubmed:year |
2004
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|
pubmed:articleTitle |
No mutations in the GATA-1 gene detected in patients with acquired essential thrombocythemia.
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pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
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