Source:http://linkedlifedata.com/resource/pubmed/id/15134305
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2004-5-11
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pubmed:abstractText |
To investigate the possibility of altered gene expression of growth factors in prenatal growth retardation, we assessed expression of the genes for insulin-like growth factor-I (IGF-I) and epidermal growth factor receptor (EGFR) by RT-PCR from human placentas at term delivery in two groups: appropriate for gestational age (AGA) and pregnancies complicated with IUGR. The placentas from IUGR gestations showed reduced IGF-I expression with a significance of p = 0.008, whereas we did not find any significant differences in EGFR gene expression.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0334-018X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17 Suppl 3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
445-50
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15134305-Female,
pubmed-meshheading:15134305-Fetal Growth Retardation,
pubmed-meshheading:15134305-Gene Expression,
pubmed-meshheading:15134305-Humans,
pubmed-meshheading:15134305-Insulin-Like Growth Factor I,
pubmed-meshheading:15134305-Placenta,
pubmed-meshheading:15134305-Pregnancy,
pubmed-meshheading:15134305-RNA, Ribosomal, 18S,
pubmed-meshheading:15134305-Receptor, Epidermal Growth Factor,
pubmed-meshheading:15134305-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Study of genetic expression of intrauterine growth factors IGF-I and EGFR in placental tissue from pregnancies with intrauterine growth retardation.
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pubmed:affiliation |
Department of Molecular Genetics, University Children's Hospital Miguel Servet, University of Zaragoza, Spain. mtcalvo@salud.aragob.es
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pubmed:publicationType |
Journal Article,
Comment
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