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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-10-13
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pubmed:abstractText |
The proto-oncogene c-KIT encodes a tyrosine kinase receptor essential during embryonic development and postnatal life. Although deregulated expression of c-KIT has been reported, its role in colorectal carcinoma remains controversial: some authors have described a correlation between c-KIT expression and colorectal cancer (CRC), while others have failed to detect the receptor in the majority of neoplasia examined. To address this question, we designed a prospective study to analyze the expression of c-KIT in normal and neoplastic colonic mucosa of the same patient.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0179-1958
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pubmed:author |
pubmed-author:BonifaziAntonio PanicciàAP,
pubmed-author:CapursoGabrieleG,
pubmed-author:CarraraAlessandroA,
pubmed-author:CassettaSaraS,
pubmed-author:CoppolaLuigiL,
pubmed-author:Delle FaveGianfrancoG,
pubmed-author:GeremiaRaffaeleR,
pubmed-author:GrassiGiovanni BattistaGB,
pubmed-author:RossiPellegrinoP,
pubmed-author:SammarcoInnocenzoI,
pubmed-author:SetteClaudioC
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
545-53
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15133698-Aged,
pubmed-meshheading:15133698-Aged, 80 and over,
pubmed-meshheading:15133698-Blotting, Western,
pubmed-meshheading:15133698-Carcinoma,
pubmed-meshheading:15133698-Colorectal Neoplasms,
pubmed-meshheading:15133698-Female,
pubmed-meshheading:15133698-Gene Expression Profiling,
pubmed-meshheading:15133698-Humans,
pubmed-meshheading:15133698-Immunohistochemistry,
pubmed-meshheading:15133698-Male,
pubmed-meshheading:15133698-Middle Aged,
pubmed-meshheading:15133698-Prospective Studies,
pubmed-meshheading:15133698-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:15133698-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Expression of the proto-oncogene c-KIT in normal and tumor tissues from colorectal carcinoma patients.
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pubmed:affiliation |
Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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