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pubmed-article:15133309pubmed:abstractTextSome traits, while naturally polychotomous, are routinely dichotomized for genetic analysis. Dichotomization, intuitively, leads to a loss of power to detect linkage, as some phenotypic variability is discarded. This paper examines this power loss in the context of a trichotomous trait.lld:pubmed
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pubmed-article:15133309pubmed:copyrightInfoCopyright 2004 S. Karger AG, Basellld:pubmed
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pubmed-article:15133309pubmed:articleTitlePower loss for linkage analysis due to the dichotomization of trichotomous phenotypes.lld:pubmed
pubmed-article:15133309pubmed:affiliationDivision of Biostatistics, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA. jon@wubios.wustl.edulld:pubmed
pubmed-article:15133309pubmed:publicationTypeJournal Articlelld:pubmed
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