Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-5-10
pubmed:abstractText
Sterol-regulatory element-binding proteins (SREBPs) regulate transcription of genes of lipid metabolism. Ceramide decreases transcriptionally active SREBP levels independently of intracellular cholesterol levels. Mechanisms of the ceramide-mediated decrease of SREBP levels were investigated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/1-Deoxynojirimycin, http://linkedlifedata.com/resource/pubmed/chemical/1-phenyl-2-palmitoylamino-3-morpholi..., http://linkedlifedata.com/resource/pubmed/chemical/2,3-N-octanoylsphingosine, http://linkedlifedata.com/resource/pubmed/chemical/2-(N-myristoylamino)-1-phenyl-1-prop..., http://linkedlifedata.com/resource/pubmed/chemical/Acyltransferases, http://linkedlifedata.com/resource/pubmed/chemical/Amidohydrolases, http://linkedlifedata.com/resource/pubmed/chemical/CCAAT-Enhancer-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Ceramides, http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, http://linkedlifedata.com/resource/pubmed/chemical/Cycloserine, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated, http://linkedlifedata.com/resource/pubmed/chemical/Fumonisins, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA Synthase, http://linkedlifedata.com/resource/pubmed/chemical/Morpholines, http://linkedlifedata.com/resource/pubmed/chemical/Myristates, http://linkedlifedata.com/resource/pubmed/chemical/N,N-dimethylsphingosine, http://linkedlifedata.com/resource/pubmed/chemical/N-caproylsphingosine, http://linkedlifedata.com/resource/pubmed/chemical/Phosphotransferases (Alcohol Group..., http://linkedlifedata.com/resource/pubmed/chemical/Propanolamines, http://linkedlifedata.com/resource/pubmed/chemical/Serine C-Palmitoyltransferase, http://linkedlifedata.com/resource/pubmed/chemical/Sphingolipids, http://linkedlifedata.com/resource/pubmed/chemical/Sphingosine, http://linkedlifedata.com/resource/pubmed/chemical/Sterol Regulatory Element Binding..., http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/fumonisin B1, http://linkedlifedata.com/resource/pubmed/chemical/miglustat, http://linkedlifedata.com/resource/pubmed/chemical/sphingosine kinase, http://linkedlifedata.com/resource/pubmed/chemical/thermozymocidin
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
943-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:15132973-1-Deoxynojirimycin, pubmed-meshheading:15132973-Acyltransferases, pubmed-meshheading:15132973-Amidohydrolases, pubmed-meshheading:15132973-Animals, pubmed-meshheading:15132973-CCAAT-Enhancer-Binding Proteins, pubmed-meshheading:15132973-CHO Cells, pubmed-meshheading:15132973-Ceramides, pubmed-meshheading:15132973-Cholesterol, pubmed-meshheading:15132973-Cricetinae, pubmed-meshheading:15132973-Cricetulus, pubmed-meshheading:15132973-Cycloserine, pubmed-meshheading:15132973-DNA-Binding Proteins, pubmed-meshheading:15132973-Enzyme Induction, pubmed-meshheading:15132973-Fatty Acids, Monounsaturated, pubmed-meshheading:15132973-Fumonisins, pubmed-meshheading:15132973-Genes, Reporter, pubmed-meshheading:15132973-Hydroxymethylglutaryl-CoA Synthase, pubmed-meshheading:15132973-Morpholines, pubmed-meshheading:15132973-Myristates, pubmed-meshheading:15132973-Phosphotransferases (Alcohol Group Acceptor), pubmed-meshheading:15132973-Propanolamines, pubmed-meshheading:15132973-RNA Processing, Post-Transcriptional, pubmed-meshheading:15132973-Serine C-Palmitoyltransferase, pubmed-meshheading:15132973-Sphingolipids, pubmed-meshheading:15132973-Sphingosine, pubmed-meshheading:15132973-Sterol Regulatory Element Binding Protein 1, pubmed-meshheading:15132973-Transcription, Genetic, pubmed-meshheading:15132973-Transcription Factors, pubmed-meshheading:15132973-Transfection
pubmed:year
2004
pubmed:articleTitle
Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein.
pubmed:affiliation
Department of Pathology, Columbia University, New York, NY 10032, USA. tpw7@columbia.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't