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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-9-29
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pubmed:abstractText |
Fifty patients with infections associated with hematological disorders were treated with ceftazidime (CAZ). Among them 44 cases were evaluable, including 21 with acute leukemia, 17 with malignant lymphoma, and 6 with other hematological disorders. Excellent responses were observed in 15 patients (34.1%) and good responses in 15 (34.1%), with an overall efficacy rate of 68.2%. The efficacy rate among sepsis and suspected sepsis cases was 67.6%. This treatment was also effective in 7 of 10 cases in which neutrophil counts were less than 500/mm3 through the course of administration. Laboratory abnormalities included mild eosinophilia in 1 case, slight elevation of GOT in 1 case and slight elevation of GPT in 1 case. These results suggest that CAZ is an effective and safe antibiotics for the treatment of infections in patients with hematological disorders.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0368-2781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
523-9
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:1512938-Adult,
pubmed-meshheading:1512938-Aged,
pubmed-meshheading:1512938-Aged, 80 and over,
pubmed-meshheading:1512938-Ceftazidime,
pubmed-meshheading:1512938-Drug Evaluation,
pubmed-meshheading:1512938-Female,
pubmed-meshheading:1512938-Humans,
pubmed-meshheading:1512938-Immunocompromised Host,
pubmed-meshheading:1512938-Leukemia,
pubmed-meshheading:1512938-Leukocyte Count,
pubmed-meshheading:1512938-Lymphoma,
pubmed-meshheading:1512938-Male,
pubmed-meshheading:1512938-Middle Aged,
pubmed-meshheading:1512938-Neutrophils,
pubmed-meshheading:1512938-Pneumonia,
pubmed-meshheading:1512938-Sepsis
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pubmed:year |
1992
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pubmed:articleTitle |
[Clinical evaluation of ceftazidime monotherapy for infections complicated with hematological disorders].
|
pubmed:affiliation |
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine.
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pubmed:publicationType |
Journal Article,
English Abstract
|