rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-5-6
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pubmed:abstractText |
Unilateral microdialysis-perfusion of the preoptic area with 50 microM muscimol decreased the sleep period of rats to less than 3% of the baseline value over a 90 min period before death (p = 0.018 by Wilcoxon signed-rank test). These rats showed the expression of FOS in 36% of the orexin neurons located in the perifornical/lateral hypothalamic areas on the side ipsilateral to the perfusion site, but in only 3% of the orexin neurons on the side contralateral to it (p = 0.018 by Wilcoxon signed-rank test). These results suggest that subpopulations of the preoptic neurons give an inhibitory tone to the activities of the orexin neurons in the perifornical/lateral hypothalamic areas.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0959-4965
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 Lippincott Williams and Wilkins
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pubmed:issnType |
Print
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pubmed:day |
19
|
pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1127-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15129159-Animals,
pubmed-meshheading:15129159-Arousal,
pubmed-meshheading:15129159-Carrier Proteins,
pubmed-meshheading:15129159-Gene Expression Regulation,
pubmed-meshheading:15129159-Injections, Intraventricular,
pubmed-meshheading:15129159-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15129159-Male,
pubmed-meshheading:15129159-Muscimol,
pubmed-meshheading:15129159-Neurons,
pubmed-meshheading:15129159-Neuropeptides,
pubmed-meshheading:15129159-Perfusion,
pubmed-meshheading:15129159-Preoptic Area,
pubmed-meshheading:15129159-Proto-Oncogene Proteins c-fos,
pubmed-meshheading:15129159-Rats,
pubmed-meshheading:15129159-Rats, Sprague-Dawley,
pubmed-meshheading:15129159-Sleep
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pubmed:year |
2004
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pubmed:articleTitle |
FOS expression in orexin neurons following muscimol perfusion of preoptic area.
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pubmed:affiliation |
Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka 569-8686, Japan. knssat@yahoo.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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