rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6 Pt 1
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pubmed:dateCreated |
2004-5-5
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pubmed:abstractText |
We investigated whether antisense (AS) oligodeoxynucleotide (ODN) targeting the clusterin gene enhances the cytotoxic effect of gemcitabine in human bladder cancer KoTCC-1 cells in vitro and in vivo, and evaluated the usefulness of the combined administration of AS clusterin ODN and gemcitabine using an intraperitoneal tumor cell injection model.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic,
http://linkedlifedata.com/resource/pubmed/chemical/CLU protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Clu protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Clusterin,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Molecular Chaperones,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Oligodeoxyribonucleotides, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/gemcitabine
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-5347
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
171
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2477-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15126879-Administration, Intravesical,
pubmed-meshheading:15126879-Animals,
pubmed-meshheading:15126879-Antimetabolites, Antineoplastic,
pubmed-meshheading:15126879-Cell Line, Tumor,
pubmed-meshheading:15126879-Clusterin,
pubmed-meshheading:15126879-Combined Modality Therapy,
pubmed-meshheading:15126879-Deoxycytidine,
pubmed-meshheading:15126879-Female,
pubmed-meshheading:15126879-Glycoproteins,
pubmed-meshheading:15126879-Humans,
pubmed-meshheading:15126879-Mice,
pubmed-meshheading:15126879-Mice, Inbred BALB C,
pubmed-meshheading:15126879-Molecular Chaperones,
pubmed-meshheading:15126879-Neoplasm Proteins,
pubmed-meshheading:15126879-Oligodeoxyribonucleotides, Antisense,
pubmed-meshheading:15126879-Urinary Bladder Neoplasms
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pubmed:year |
2004
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pubmed:articleTitle |
Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligodeoxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer kotcc-1 cells.
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pubmed:affiliation |
Department of Urology, Hyogo Medical Center for Adults, Akashi and Kobe University School of Medicine, Kobe, Japan.
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pubmed:publicationType |
Journal Article
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