Source:http://linkedlifedata.com/resource/pubmed/id/15122179
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2004-5-3
|
| pubmed:abstractText |
We assessed the effects of implantation of Myosplint (Myocor, Maple Grove, Minn), a device that changes left ventricular (LV) cross-sectional shape from circular to bilobar, on regional LV function. A total of 10 open-chest dogs with tachycardia-induced cardiomyopathy were studied before and after Myosplint implantation. LV cross-sectional epicardial echocardiography at the papillary muscle level was performed along with acquisition of hemodynamic data. LV normalized thickening, fractional thickening, end-diastolic thickness, and end-diastolic curvatures were calculated for 10 LV segments. Myosplint implantation did not affect LV hemodynamics, but decreased average end-diastolic curvature (P <.0001) and increased its segmental heterogeneity (P <.0001). There was no change in average fractional thickening, whereas normalized thickening increased (P =.05). In contrast, segmental heterogeneity of both normalized and fractional thickening increased (P =.02 and P =.01, respectively). Structural modeling confirmed that Myosplint implantation increases regional stress heterogeneity and curvature heterogeneity. LV cross-sectional shape markedly affects regional LV performance.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0894-7317
|
| pubmed:author |
pubmed-author:DeserrannoDimitriD,
pubmed-author:DoiKazuyoshiK,
pubmed-author:FukamachiKiyotakaK,
pubmed-author:GreenbergNeil LNL,
pubmed-author:InoueMasahiroM,
pubmed-author:McCarthyPatrick MPM,
pubmed-author:OchiaiYoshieY,
pubmed-author:Popovi?Zoran BZB,
pubmed-author:QinJianxinJ,
pubmed-author:SaracinoGiuseppeG,
pubmed-author:SchenkSorenS,
pubmed-author:ShiotaTakahiroT,
pubmed-author:TakagakiMasamiM,
pubmed-author:ThomasJames DJD,
pubmed-author:YangHuaH
|
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
411-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
2004
|
| pubmed:articleTitle |
Echocardiographic assessment of regional ventricular function after device-based change of left ventricular shape.
|
| pubmed:affiliation |
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|