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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-9-28
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pubmed:abstractText |
Polynesians from five distinct island groups were studied with DNA probe alpha 3'HVR, a highly polymorphic VNTR (variable number of tandem repeats) minisatellite region associated with the alpha-globin gene cluster. Results showed a paucity of genetic heterozygosity together with clustering of alpha 3'HVR alleles with alpha-globin DNA haplotypes and alpha-globin gene rearrangements. This restricted diversity is consistent with population bottlenecks in the colonization of Polynesia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-5652
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
157-61
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1511993-Alleles,
pubmed-meshheading:1511993-Chromosome Mapping,
pubmed-meshheading:1511993-DNA,
pubmed-meshheading:1511993-Genetic Markers,
pubmed-meshheading:1511993-Genetic Variation,
pubmed-meshheading:1511993-Globins,
pubmed-meshheading:1511993-Humans,
pubmed-meshheading:1511993-Polymorphism, Genetic,
pubmed-meshheading:1511993-Polynesia,
pubmed-meshheading:1511993-Repetitive Sequences, Nucleic Acid
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pubmed:year |
1992
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pubmed:articleTitle |
Limited genetic diversity in polynesians reflected in the highly polymorphic 3'HVR alpha-globin gene marker.
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pubmed:affiliation |
Department of Molecular Genetics, Royal Prince Alfred Hospital, Camperdown, N.S.W., Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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