Source:http://linkedlifedata.com/resource/pubmed/id/15118944
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-4-30
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pubmed:abstractText |
Functional brain imaging with nonfluent aphasia patients has shown increased cortical activation (perhaps "overactivation") in right (R) hemisphere language homologues. These areas of overactivation may represent a maladaptive strategy that interferes with, rather than promotes, aphasia recovery. Repetitive transcranial magnetic stimulation (rTMS) is a painless, noninvasive procedure that utilizes magnetic fields to create electric currents in discrete brain areas affecting about a 1-cm square area of cortex. Slow frequency, 1 Hz rTMS reduces cortical excitability. When rTMS is applied to an appropriate cortical region, it may suppress the possible overactivation and thus modulate a distributed neural network for language. We provide information on rTMS and report preliminary results following rTMS application to R Broca's area (posterior, R pars triangularis) in four stroke patients with nonfluent aphasia (5-11 years after left hemisphere stroke). Following 10 rTMS treatments, significant improvement in naming pictures was observed. This form of rTMS may provide a novel, complementary treatment for aphasia.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0734-0478
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pubmed:author |
pubmed-author:DoronKarlK,
pubmed-author:FregniFelipeF,
pubmed-author:KurlandJacquieJ,
pubmed-author:MartinPaula IPI,
pubmed-author:NaeserMargaret AMA,
pubmed-author:NicholasMarjorieM,
pubmed-author:Pascual-LeoneAlvaroA,
pubmed-author:SeekinsHeidiH,
pubmed-author:TheoretHugoH,
pubmed-author:TormosJose MariaJM
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pubmed:copyrightInfo |
Copyright 2004 Thieme Medical Publishers, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-91
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15118944-Aphasia,
pubmed-meshheading:15118944-Dominance, Cerebral,
pubmed-meshheading:15118944-Electric Stimulation,
pubmed-meshheading:15118944-Frontal Lobe,
pubmed-meshheading:15118944-Humans,
pubmed-meshheading:15118944-Language,
pubmed-meshheading:15118944-Mental Processes,
pubmed-meshheading:15118944-Reaction Time,
pubmed-meshheading:15118944-Transcranial Magnetic Stimulation
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pubmed:year |
2004
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pubmed:articleTitle |
Transcranial magnetic stimulation as a complementary treatment for aphasia.
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pubmed:affiliation |
Boston University School of Medicine and VA Boston Healthcare System, Neuroimaging/Aphasia Research, Transcranial Magnetic Stimulation/Aphasia Research and Harold Goodglass Aphasia Research Center, Boston, Massachusetts 02130,USA. paulak@bu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Review
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