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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1992-9-28
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pubmed:databankReference |
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pubmed:abstractText |
A gene (lmsod) encoding superoxide dismutase (SOD; EC 1.15.1.1) of the facultative intracellular pathogen, Listeria monocytogenes, was cloned by functional complementation of an SOD-deficient Escherichia coli mutant. The nucleotide sequence was determined and the deduced amino acid (aa) sequence (202 aa) showed close similarity to manganese-containing SOD's from other organisms. Subunits of the recombinant L. monocytogenes SOD (re-SOD) and of both E. coli SODs formed enzymatically active hybrid enzymes in vivo. DNA/DNA-hybridization experiments showed that this type of recombinant re-sod gene is conserved within the genus Listeria.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
118
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pubmed:geneSymbol |
lmsod
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
121-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1511873-Amino Acid Sequence,
pubmed-meshheading:1511873-Base Sequence,
pubmed-meshheading:1511873-Cloning, Molecular,
pubmed-meshheading:1511873-DNA, Bacterial,
pubmed-meshheading:1511873-Escherichia coli,
pubmed-meshheading:1511873-Genes, Bacterial,
pubmed-meshheading:1511873-Genetic Complementation Test,
pubmed-meshheading:1511873-Listeria monocytogenes,
pubmed-meshheading:1511873-Manganese,
pubmed-meshheading:1511873-Molecular Sequence Data,
pubmed-meshheading:1511873-Nucleic Acid Hybridization,
pubmed-meshheading:1511873-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1511873-Superoxide Dismutase
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pubmed:year |
1992
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pubmed:articleTitle |
A gene encoding a superoxide dismutase of the facultative intracellular bacterium Listeria monocytogenes.
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pubmed:affiliation |
Theodor-Boveri-Institut für Biowissenschaften, Biozentrum, Universität Würzburg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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