Linked Life Data

15117545

Source:http://linkedlifedata.com/resource/pubmed/id/15117545

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-4-30
pubmed:abstractText
Panax ginseng C.A. Meyer has been traditionally used for the prevention and treatment of various chronic diseases and infections. Ginseng marc is a fibrous and insoluble by-product remaining after the extraction process of ginseng. In this research an extrusion process was employed to disintegrate the insoluble ginseng marc structure, and water-soluble ginseng marc polysaccharide (GMP) was isolated. GMP was examined for immunomodulatory effects in murine peritoneal macrophages. GMP significantly increased the lysosomal phosphatase activity and the phagocytic index of peritoneal macrophages (P<.05). The peritoneal macrophages treated with GMP also produced significantly more H(2)O(2) and nitrite than the control without GMP treatment (P<.05). In addition, GMP (100 microg/mL) significantly increased the cell viability of peritoneal macrophages (P<.05). These results suggest that GMP is an effective nonspecific immunomodulatory agent, and its immunostimulating effects may be due to its ability to stimulate the production of reactive oxygen intermediates.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1096-620X
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Immunomodulating activities of polysaccharides isolated from Panax ginseng.
pubmed:affiliation
Department of Biotechnology & Bioproducts Research Center, Yonsei University, Seodaemun-gu, Seoul, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't