|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010592,
umls-concept:C0021079,
umls-concept:C0021080,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0072980,
umls-concept:C0085149,
umls-concept:C0370231,
umls-concept:C0596873,
umls-concept:C0936012,
umls-concept:C1280500,
umls-concept:C1879547
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2004-4-28
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|
pubmed:abstractText |
Whole-blood analysis of lymphocyte function was used to investigate the pharmacodynamic (PD) interaction of sirolimus (SRL) with cyclosporine (CsA) or tacrolimus (TRL) in vitro and to determine the relation between PD and pharmacokinetics (PK) of SRL in an in vivo rat model.
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|
pubmed:commentsCorrections |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0041-1337
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:day |
27
|
|
pubmed:volume |
77
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1154-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15114077-Animals,
pubmed-meshheading:15114077-Cyclosporine,
pubmed-meshheading:15114077-Drug Synergism,
pubmed-meshheading:15114077-Immunosuppressive Agents,
pubmed-meshheading:15114077-Lymphocyte Activation,
pubmed-meshheading:15114077-Lymphocytes,
pubmed-meshheading:15114077-Male,
pubmed-meshheading:15114077-Rats,
pubmed-meshheading:15114077-Rats, Inbred Lew,
pubmed-meshheading:15114077-Sirolimus,
pubmed-meshheading:15114077-Tacrolimus
|
|
pubmed:year |
2004
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|
pubmed:articleTitle |
Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood.
|
|
pubmed:affiliation |
University of Leipzig, Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany. bartenm@medizin.uni-leipzig.de
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't
|
