Linked Life Data

15113097

Source:http://linkedlifedata.com/resource/pubmed/id/15113097

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-4-28
pubmed:abstractText
To find genes that underlie disease susceptibilities, genome-wide single nucleotide polymorphisms (SNPs) have been analyzed using high-throughput matrix assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS). As a proof-of-concept for this approach, gene regions have been identified that were previously associated by others with certain diseases or traits. On the same technology platform, accurate and absolute transcriptional profiling can be performed and applied to allele expression analysis. Here, we provide a brief review of the technology and its applications to disease gene discovery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1535-3893
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-27
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Mining disease susceptibility genes through SNP analyses and expression profiling using MALDI-TOF mass spectrometry.
pubmed:affiliation
Sequenom Inc., 3595 John Hopkins Court, San Diego, California 92121, USA.
pubmed:publicationType
Journal Article