Linked Life Data

15110333

Source:http://linkedlifedata.com/resource/pubmed/id/15110333

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2004-4-27
pubmed:abstractText
Changes of serum C-reactive protein (CRP) levels in rainbow trout (Oncorhynchus mykiss) were studied after exposure to formalin, metriphonate or potassium permanganate, which are used in aquaculture as anti-ectoparasitic chemicals. The CRP level in normal trout sera is 88+/-5 microg ml(-1) according to sandwich enzyme-linked immunosorbent assay. CRP levels increased to a maximum at six or nine days after exposure to formalin for 3.5 h at 300 ppm or 9.5 h at 30 ppm, respectively; these levels are 4.3 and 18 times higher than normal. At 18 days after treatment, the CRP level had decreased to significantly below the normal level. After exposure to metriphonate (0.4 ppm for 30 min), the CRP level increased significantly to a maximum at three days after exposure (9.9 times higher than normal), then decreased to below normal. With exposure to potassium permanganate at 40 ppm for 45 min, fish showed significantly lower CRP levels than the normal level at 14 days after exposure. Fish reared at a water temperature of 16.5-19.5 degrees C showed significantly higher CRP levels than those reared at 13 degrees C. Measurement of CRP levels in trout serum can be used as a bioindicator of the health condition of the fish.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1050-4648
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
589-97
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15110333-Analysis of Variance, pubmed-meshheading:15110333-Animals, pubmed-meshheading:15110333-Antiparasitic Agents, pubmed-meshheading:15110333-Aquaculture, pubmed-meshheading:15110333-C-Reactive Protein, pubmed-meshheading:15110333-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:15110333-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:15110333-Formaldehyde, pubmed-meshheading:15110333-Gene Expression Regulation, pubmed-meshheading:15110333-Immune Sera, pubmed-meshheading:15110333-Mice, pubmed-meshheading:15110333-Mice, Inbred BALB C, pubmed-meshheading:15110333-Oncorhynchus mykiss, pubmed-meshheading:15110333-Potassium Permanganate, pubmed-meshheading:15110333-Temperature, pubmed-meshheading:15110333-Time Factors, pubmed-meshheading:15110333-Trichlorfon
pubmed:year
2004
pubmed:articleTitle
Changes of C-reactive protein levels in rainbow trout (Oncorhynchus mykiss) sera after exposure to anti-ectoparasitic chemicals used in aquaculture.
pubmed:affiliation
Laboratory of Veterinary Immunology, Course of Veterinary Science, Graduate School of Agriculture and Biological Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. kodama@vet.osaka-u.ac.jp
pubmed:publicationType
Journal Article, Comparative Study