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15109624
Source:
http://linkedlifedata.com/resource/pubmed/id/15109624
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0220781
,
umls-concept:C0279516
,
umls-concept:C0441655
,
umls-concept:C1449860
,
umls-concept:C1883254
pubmed:issue
10
pubmed:dateCreated
2004-4-27
pubmed:abstractText
A series of novel 6-O-arylpropargyl-9-oxime-ketolides was synthesized and evaluated against various pathogens. These new compounds show promising in vitro antibacterial potency and in vivo efficacy against macrolide resistant strains.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents
,
http://linkedlifedata.com/resource/pubmed/chemical/Ketolides
,
http://linkedlifedata.com/resource/pubmed/chemical/Macrolides
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0960-894X
pubmed:author
pubmed-author:BeebeXeniaX
,
pubmed-author:BuiMai HMH
,
pubmed-author:DjuricStevan WSW
,
pubmed-author:MaZhenkunZ
,
pubmed-author:MittenMichael JMJ
,
pubmed-author:NiliusAngela MAM
,
pubmed-author:YangFanF
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2417-21
pubmed:meshHeading
pubmed-meshheading:15109624-Animals
,
pubmed-meshheading:15109624-Anti-Bacterial Agents
,
pubmed-meshheading:15109624-Disease Models, Animal
,
pubmed-meshheading:15109624-Drug Resistance, Bacterial
,
pubmed-meshheading:15109624-Haemophilus influenzae
,
pubmed-meshheading:15109624-Ketolides
,
pubmed-meshheading:15109624-Macrolides
,
pubmed-meshheading:15109624-Rats
,
pubmed-meshheading:15109624-Respiratory Tract Infections
,
pubmed-meshheading:15109624-Staphylococcus
,
pubmed-meshheading:15109624-Structure-Activity Relationship
pubmed:year
2004
pubmed:articleTitle
Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides.
pubmed:affiliation
Infectious Disease Research, Abbott Laboratories, Abbott Park, IL 60064, USA. xenia.b.searle@abbott.com
pubmed:publicationType
Journal Article