Source:http://linkedlifedata.com/resource/pubmed/id/15107558
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2004-4-26
|
pubmed:abstractText |
To know the genetic changes of feline immunodeficiency virus (FIV) in long-term infection in cats, we inoculated three specific pathogen-free cats with FIV isolates and determined a partial env sequence covering the V3-V5 region. In 2 cats infected with subtype B strains TM1 and TM2, only one amino acid change in region V3 was observed at 9 years post infection (y.p.i.), and no nucleotide substitutions were observed between 9 and 10 y.p.i., indicating that these strains are genetically stable. On the other hand, in a cat infected with subtype A strain Petaluma at 8.7 y.p.i., 3 nucleotide insertions (one amino acid insertion) in region V5, and 1 synonymous nucleotide substitution and 2 non-synonymous nucleotide substitutions in region V5, were observed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0916-7250
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
66
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
287-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15107558-Amino Acid Sequence,
pubmed-meshheading:15107558-Animals,
pubmed-meshheading:15107558-Cat Diseases,
pubmed-meshheading:15107558-Cats,
pubmed-meshheading:15107558-Genes, env,
pubmed-meshheading:15107558-Genome, Viral,
pubmed-meshheading:15107558-Genomic Instability,
pubmed-meshheading:15107558-Immunodeficiency Virus, Feline,
pubmed-meshheading:15107558-Lentivirus Infections,
pubmed-meshheading:15107558-Molecular Sequence Data,
pubmed-meshheading:15107558-Mutation,
pubmed-meshheading:15107558-Sequence Analysis, DNA
|
pubmed:year |
2004
|
pubmed:articleTitle |
High genetic stability of TM1 and TM2 strains of subtype B feline immunodeficiency virus in long-term infection.
|
pubmed:affiliation |
Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|