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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-4-22
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pubmed:abstractText |
A major obstacle in the treatment of ovarian carcinoma is the intrinsic/acquired resistance to cisplatin-based chemotherapy. Cu-transporting ATPase (ATP7B) has been reported to be associated with cisplatin resistance in vitro. However, the clinical significance of this transporter has not previously been addressed. Our goal was to investigate ATP7B expression in ovarian carcinoma and whether its expression correlates with prognosis and reduced responsiveness to cisplatin treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:ItohKiyoshiK,
pubmed-author:KanzakiAtsukoA,
pubmed-author:MiyazakiKohjiK,
pubmed-author:MutohMasatoM,
pubmed-author:NakayamaKentaroK,
pubmed-author:NeamatiNouriN,
pubmed-author:OgawaKenjiK,
pubmed-author:SugiyamaToshihiroT,
pubmed-author:TakebayashiYujiY,
pubmed-author:TakenoshitaSeiichiS,
pubmed-author:TeradaKunihikoK,
pubmed-author:YaegashiNobuoN
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2804-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15102688-Adenosine Triphosphatases,
pubmed-meshheading:15102688-Adult,
pubmed-meshheading:15102688-Aged,
pubmed-meshheading:15102688-Antineoplastic Agents,
pubmed-meshheading:15102688-Base Sequence,
pubmed-meshheading:15102688-Biological Transport,
pubmed-meshheading:15102688-Carcinoma,
pubmed-meshheading:15102688-Cation Transport Proteins,
pubmed-meshheading:15102688-Cisplatin,
pubmed-meshheading:15102688-DNA Mutational Analysis,
pubmed-meshheading:15102688-Female,
pubmed-meshheading:15102688-Humans,
pubmed-meshheading:15102688-Immunohistochemistry,
pubmed-meshheading:15102688-Middle Aged,
pubmed-meshheading:15102688-Molecular Sequence Data,
pubmed-meshheading:15102688-Multivariate Analysis,
pubmed-meshheading:15102688-Ovarian Neoplasms,
pubmed-meshheading:15102688-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:15102688-Prognosis,
pubmed-meshheading:15102688-Proportional Hazards Models,
pubmed-meshheading:15102688-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15102688-Time Factors,
pubmed-meshheading:15102688-Treatment Outcome,
pubmed-meshheading:15102688-Tumor Suppressor Protein p53
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pubmed:year |
2004
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pubmed:articleTitle |
Prognostic value of the Cu-transporting ATPase in ovarian carcinoma patients receiving cisplatin-based chemotherapy.
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pubmed:affiliation |
Department of Obstetrics, Shimane Medical University, Izumo, Japan.
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pubmed:publicationType |
Journal Article
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