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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-4-22
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pubmed:abstractText |
Overexpression of MUC1 and cytosolic interaction of the mucin with beta-catenin are claimed to be involved in colorectal carcinogenesis. In vitro data published recently suggest that MUC1 overexpression results in an increase of steady state levels of nuclear beta-catenin. We tried to elucidate the coexpression of both molecules in colorectal cancer to demonstrate possible correlations with clinical, pathological, and prognostic data.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2790-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15102686-Adult,
pubmed-meshheading:15102686-Aged,
pubmed-meshheading:15102686-Aged, 80 and over,
pubmed-meshheading:15102686-Cell Nucleus,
pubmed-meshheading:15102686-Colorectal Neoplasms,
pubmed-meshheading:15102686-Cytoskeletal Proteins,
pubmed-meshheading:15102686-Disease Progression,
pubmed-meshheading:15102686-Female,
pubmed-meshheading:15102686-Humans,
pubmed-meshheading:15102686-Immunohistochemistry,
pubmed-meshheading:15102686-Male,
pubmed-meshheading:15102686-Middle Aged,
pubmed-meshheading:15102686-Mucin-1,
pubmed-meshheading:15102686-Neoplasm Invasiveness,
pubmed-meshheading:15102686-Prognosis,
pubmed-meshheading:15102686-Proportional Hazards Models,
pubmed-meshheading:15102686-Signal Transduction,
pubmed-meshheading:15102686-Time Factors,
pubmed-meshheading:15102686-Trans-Activators,
pubmed-meshheading:15102686-Treatment Outcome,
pubmed-meshheading:15102686-beta Catenin
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pubmed:year |
2004
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pubmed:articleTitle |
MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis.
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pubmed:affiliation |
Institute of Pathology, University of Cologne, Cologne, Germany. s-e.baldus@uni-koeln.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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