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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-4-22
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pubmed:abstractText |
INGN 201 (Ad-p53) is a replication-defective adenoviral vector that encodes a wild-type p53 gene driven by the cytomegalovirus promoter. INGN 201 has been shown to have antitumoral activity against human prostate cancer cell lines. This study was undertaken to determine the safety of INGN 201 in patients with locally advanced prostate cancer, to assess transgene expression, and to evaluate antitumoral activity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BrisbayShawn MSM,
pubmed-author:DoKim-AnhKA,
pubmed-author:EvansRobert BRB,
pubmed-author:HossanElizabeth AEA,
pubmed-author:JacobsonMarc GMG,
pubmed-author:LogothetisChristopher JCJ,
pubmed-author:McDonnellTimothy JTJ,
pubmed-author:MerrittJames AJA,
pubmed-author:ParkerKarenK,
pubmed-author:PettawayCurtis ACA,
pubmed-author:PistersLouis LLL,
pubmed-author:SotoCindyC,
pubmed-author:SteinerMitchell SMS,
pubmed-author:StephensL CliftonLC,
pubmed-author:TroncosoPatriciaP,
pubmed-author:WangXuemeiX,
pubmed-author:WoodChristopher GCG
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2587-93
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15102659-Adenoviridae,
pubmed-meshheading:15102659-Aged,
pubmed-meshheading:15102659-Apoptosis,
pubmed-meshheading:15102659-DNA Fragmentation,
pubmed-meshheading:15102659-Disease Progression,
pubmed-meshheading:15102659-Disease-Free Survival,
pubmed-meshheading:15102659-Gene Therapy,
pubmed-meshheading:15102659-Genes, p53,
pubmed-meshheading:15102659-Genetic Vectors,
pubmed-meshheading:15102659-Humans,
pubmed-meshheading:15102659-Immunohistochemistry,
pubmed-meshheading:15102659-In Situ Nick-End Labeling,
pubmed-meshheading:15102659-Male,
pubmed-meshheading:15102659-Middle Aged,
pubmed-meshheading:15102659-Prostatic Neoplasms,
pubmed-meshheading:15102659-Time Factors,
pubmed-meshheading:15102659-Transgenes,
pubmed-meshheading:15102659-Treatment Outcome,
pubmed-meshheading:15102659-Tumor Suppressor Protein p53
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pubmed:year |
2004
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pubmed:articleTitle |
Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancer.
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pubmed:affiliation |
Department of Urology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. lpisters@mdanderson.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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