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rdf:type |
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lifeskim:mentions |
umls-concept:C0023810,
umls-concept:C0028128,
umls-concept:C0033268,
umls-concept:C0034693,
umls-concept:C0151763,
umls-concept:C0205263,
umls-concept:C0227525,
umls-concept:C0332120,
umls-concept:C0439851,
umls-concept:C1292733,
umls-concept:C1552596,
umls-concept:C1704410,
umls-concept:C1947931
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pubmed:issue |
2
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pubmed:dateCreated |
2004-4-21
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pubmed:abstractText |
The role of nitric oxide (NO) in lipopolysaccharide (LPS) tolerance in the liver has been investigated in a number of previous studies, but it is still not clear whether NO is cytotoxic or cytoprotective. The aims of this study were to investigate whether low-dose LPS (LLPS)-induced hepatic production of NO is beneficial and to clarify the origins of cytoprotective NO-producing cells in the liver during LPS tolerance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-4804
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pubmed:author |
pubmed-author:AsamaToshiyukiT,
pubmed-author:AyabeTokiyoshiT,
pubmed-author:ChisatoNaoyukiN,
pubmed-author:EbisawaYoshiakiY,
pubmed-author:IshikawaKazushiK,
pubmed-author:IwamotoJunJ,
pubmed-author:KasaiShinichiS,
pubmed-author:KohgoYutakaY,
pubmed-author:KonoToruT,
pubmed-author:SugawaraMutsubuM,
pubmed-author:YonedaMasashiM
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15100007-Animals,
pubmed-meshheading:15100007-Dose-Response Relationship, Drug,
pubmed-meshheading:15100007-Enzyme Inhibitors,
pubmed-meshheading:15100007-Fluorescein,
pubmed-meshheading:15100007-Indicators and Reagents,
pubmed-meshheading:15100007-Kupffer Cells,
pubmed-meshheading:15100007-Lipopolysaccharides,
pubmed-meshheading:15100007-Liver Diseases,
pubmed-meshheading:15100007-Male,
pubmed-meshheading:15100007-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:15100007-Nitric Oxide,
pubmed-meshheading:15100007-Nitric Oxide Synthase,
pubmed-meshheading:15100007-Rats,
pubmed-meshheading:15100007-Rats, Wistar
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pubmed:year |
2004
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pubmed:articleTitle |
Direct evidence that induced nitric oxide production in hepatocytes prevents liver damage during lipopolysaccharide tolerance in rats.
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pubmed:affiliation |
Department of Surgery II, Asahikawa Medical College, Asahikawa, Hokkaido, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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