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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-4-20
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pubmed:abstractText |
Recent clinical and imaging studies have raised the hypothesis that patients with multiple sclerosis (MS) and the apolipoprotein E (ApoE) epsilon4 allele may have a more severe disease course than those without the ApoE epsilon4 allele. This seems to be related to more extensive tissue destruction and less efficient neuronal maintenance and repair in ApoE epsilon4 carriers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-9942
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
536-40
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15096402-Adult,
pubmed-meshheading:15096402-Alleles,
pubmed-meshheading:15096402-Apolipoprotein E4,
pubmed-meshheading:15096402-Apolipoproteins E,
pubmed-meshheading:15096402-Atrophy,
pubmed-meshheading:15096402-Brain,
pubmed-meshheading:15096402-Disability Evaluation,
pubmed-meshheading:15096402-Female,
pubmed-meshheading:15096402-Genotype,
pubmed-meshheading:15096402-Heterozygote Detection,
pubmed-meshheading:15096402-Humans,
pubmed-meshheading:15096402-Image Enhancement,
pubmed-meshheading:15096402-Image Processing, Computer-Assisted,
pubmed-meshheading:15096402-Magnetic Resonance Imaging,
pubmed-meshheading:15096402-Male,
pubmed-meshheading:15096402-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:15096402-Statistics as Topic
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pubmed:year |
2004
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pubmed:articleTitle |
Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis.
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pubmed:affiliation |
Department of Neurological and Behavioral Sciences, University of Siena, Siena, Italy. destefano@unisi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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