Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-4-20
pubmed:abstractText
Comorbidity of normal pressure hydrocephalus (NPH) and Alzheimer's disease (AD) is not uncommon. However, few studies have reported the clinical courses of these patients in depth. A 73-year-old woman was confirmed to have AD by a biopsy performed during a shunt operation for NPH after a head trauma. She was followed for 4 years using serial neuropsychological tests and positron emission tomography (PET). Her clinical symptoms remained improved for 2.5 years and then declined. The 1-year minus the presurgical PET scan highlighted the bilateral frontal area, basal ganglia, and thalamus, which may reflect brain regions associated with the improvement of hydrocephalic dementia. On the other hand, the 1-year minus the 4-year scan highlighted the bilateral temporoparietal area and the posterior cingulate gyrus, which may reflect brain regions associated with the aggravation of AD. This subtraction method may be useful for monitoring the clinical course in patients with NPH and AD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1051-2284
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
170-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:15095564-Aged, pubmed-meshheading:15095564-Alzheimer Disease, pubmed-meshheading:15095564-Basal Ganglia, pubmed-meshheading:15095564-Biopsy, pubmed-meshheading:15095564-Brain, pubmed-meshheading:15095564-Cerebral Cortex, pubmed-meshheading:15095564-Dementia, pubmed-meshheading:15095564-Dominance, Cerebral, pubmed-meshheading:15095564-Energy Metabolism, pubmed-meshheading:15095564-Female, pubmed-meshheading:15095564-Follow-Up Studies, pubmed-meshheading:15095564-Humans, pubmed-meshheading:15095564-Hydrocephalus, Normal Pressure, pubmed-meshheading:15095564-Neurologic Examination, pubmed-meshheading:15095564-Neuropsychological Tests, pubmed-meshheading:15095564-Postoperative Complications, pubmed-meshheading:15095564-Subdural Effusion, pubmed-meshheading:15095564-Thalamus, pubmed-meshheading:15095564-Tomography, Emission-Computed, pubmed-meshheading:15095564-Ventriculoperitoneal Shunt
pubmed:year
2004
pubmed:articleTitle
Serial positron emission tomography findings in a patient with hydrocephalic dementia and Alzheimer's disease.
pubmed:affiliation
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 ILwon-dong, Kangnam-ku, Seoul, Korea.
pubmed:publicationType
Journal Article, Case Reports