Source:http://linkedlifedata.com/resource/pubmed/id/15093831
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-4-19
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pubmed:abstractText |
The tail of bacteriophage T4 consists of a contractile sheath surrounding a rigid tube and terminating in a multiprotein baseplate, to which the long and short tail fibers of the phage are attached. Upon binding of the fibers to their cell receptors, the baseplate undergoes a large conformational switch, which initiates sheath contraction and culminates in transfer of the phage DNA from the capsid into the host cell through the tail tube. The baseplate has a dome-shaped sixfold-symmetric structure, which is stabilized by a garland of six short tail fibers, running around the periphery of the dome. In the center of the dome, there is a membrane-puncturing device, containing three lysozyme domains, which disrupts the intermembrane peptidoglycan layer during infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0959-440X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-80
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:15093831-Amino Acid Sequence,
pubmed-meshheading:15093831-Bacteriophage T4,
pubmed-meshheading:15093831-Cryoelectron Microscopy,
pubmed-meshheading:15093831-Crystallography, X-Ray,
pubmed-meshheading:15093831-Genes, Viral,
pubmed-meshheading:15093831-Macromolecular Substances,
pubmed-meshheading:15093831-Models, Molecular,
pubmed-meshheading:15093831-Molecular Sequence Data,
pubmed-meshheading:15093831-Viral Tail Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
The bacteriophage T4 DNA injection machine.
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pubmed:affiliation |
Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907-2054, USA. mgr@indiana.bio.purdue.edu
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pubmed:publicationType |
Journal Article,
Review
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