Source:http://linkedlifedata.com/resource/pubmed/id/15090699
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-4-19
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pubmed:abstractText |
Aortic pulse wave velocity (PWV) is a predictor of atherosclerosis. The percent mean pulse amplitude of the artery (%MPA) has been proposed as a novel marker of atherosclerosis. The present study evaluated the predictive value of PWV and the %MPA for coronary atherosclerosis. The severity of coronary atherosclerosis was evaluated using both the Gensini score and coronary calcium grade. Thirty-three patients with cardiovascular risk factors were assigned to those with significant coronary artery stenosis ((+)stenosis) group with the presence of > or = 75% coronary artery stenosis (n = 15; age: 68 +/- 7 years, mean +/- SD) or those without significant coronary artery stenosis ((-)stenosis) group (n = 18; age: 66 +/- 8 years). In each patient, the PWV and %MPA at the right brachial artery and both sides of the ankle were obtained using a non-invasive vascular screening device. The Gensini score and coronary calcium grade were higher in the +stenosis group than they were in the (-)stenosis group (P < 0.01 and P < 0.05, respectively). The brachial %MPA was lower in the (+)stenosis group than it was in the -stenosis group (P < 0.005). Both the Gensini score and the coronary calcium grade correlated with the brachial %MPA (r = 0.62, P = 0.0001 and P = 0.33, P = 0.030, respectively). Our observations suggest that brachial %MPA provides predictive values for coronary atherosclerosis in subjects at risk for cardiovascular disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0021-4868
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
231-42
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15090699-Aged,
pubmed-meshheading:15090699-Blood Flow Velocity,
pubmed-meshheading:15090699-Brachial Artery,
pubmed-meshheading:15090699-Calcinosis,
pubmed-meshheading:15090699-Cardiovascular Diseases,
pubmed-meshheading:15090699-Coronary Angiography,
pubmed-meshheading:15090699-Coronary Artery Disease,
pubmed-meshheading:15090699-Coronary Disease,
pubmed-meshheading:15090699-Coronary Stenosis,
pubmed-meshheading:15090699-Female,
pubmed-meshheading:15090699-Humans,
pubmed-meshheading:15090699-Male,
pubmed-meshheading:15090699-Middle Aged,
pubmed-meshheading:15090699-Predictive Value of Tests,
pubmed-meshheading:15090699-Pulse,
pubmed-meshheading:15090699-Risk Factors,
pubmed-meshheading:15090699-Severity of Illness Index,
pubmed-meshheading:15090699-Tomography, Spiral Computed
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pubmed:year |
2004
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pubmed:articleTitle |
Brachial arterial stiffness predicts coronary atherosclerosis in patients at risk for cardiovascular diseases.
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pubmed:affiliation |
Department of Internal Medicine I, School of Medicine, Oita Medical University, Oita, Japan.
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pubmed:publicationType |
Journal Article
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