Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2004-4-19
pubmed:abstractText
A review is given on the morphology of Acremonium chrysogenum and the biosynthesis of cephalosporin C based on the published references. Investigations are presented on the comparison of cultivation media carried out by means of shake flask cultures. The process performance of a standard cultivation in well controlled bioreactor is presented and compared with other cultivations, which were executed with the same strain and bioreactor, but with various carbon-, nitrogen- and sulphur-sources keeping the concentrations of the key components at definite levels. Also the influence of dilution and enrichment of the medium on the process performance is explored. Mathematical models for the growth of Acremonium chrysogenum and production of cephalosporin C are reviewed and their application for control of industrial processes with complex cultivation media are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0724-6145
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-45
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Investigations of the production of cephalosporin C by Acremonium chrysogenum.
pubmed:affiliation
Aventis Pharma Deutschland GmbH, Wirkstoffe, Wirkstoffproduktion Biotechnik, Industriepark Hoechst, 65926 Frankfurt am Main, Germany.
pubmed:publicationType
Journal Article, Review