Source:http://linkedlifedata.com/resource/pubmed/id/15087041
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-4-16
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pubmed:abstractText |
Studies have revealed that overexpression of p53 protein has close relation to induction of drug resistance in cancer patients and it can be used as a predictor for chemosensitivity of tumor. Recently, it has been found that specific p53 antibody (p53-Ab) presented in the serum of cancer patients with p53 protein overexpression. Furthermore, the presence of serum p53-Ab is closely correlated with p53 protein overexpression. Thus, serum p53-Ab could theoretically be useful in predicting chemosensitivity in cancer patients. In the present study, we investigated whether preoperative serum p53-Ab is correlated with the postoperative chemosensitivity of esophageal cancer, which was analyzed using in vitro drug response assay.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1000-467X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
467-70
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pubmed:dateRevised |
2009-11-3
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pubmed:meshHeading |
pubmed-meshheading:15087041-Adult,
pubmed-meshheading:15087041-Aged,
pubmed-meshheading:15087041-Antibodies,
pubmed-meshheading:15087041-Esophageal Neoplasms,
pubmed-meshheading:15087041-Female,
pubmed-meshheading:15087041-Humans,
pubmed-meshheading:15087041-Male,
pubmed-meshheading:15087041-Middle Aged,
pubmed-meshheading:15087041-Tumor Suppressor Protein p53
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pubmed:year |
2004
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pubmed:articleTitle |
[Correlation between serum p53 antibody and chemosensitivity in patient with esophageal cancer].
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pubmed:affiliation |
Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510120, PR China. wangminghui01@hotmail.com
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pubmed:publicationType |
Journal Article,
English Abstract
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