Source:http://linkedlifedata.com/resource/pubmed/id/15087028
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-4-16
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pubmed:abstractText |
Mifepristone is an effective progesterone receptor antagonist. It was reported that mifepristone can inhibit the growth of ovarian carcinoma cells either in vitro or in vivo, but the exact mechanism is unknown. The effect of mifepristone on the growth, apoptosis and cis-platinum (DDP)-sensitivity of chemo-resistant ovarian carcinoma cell lines have scarcely been reported. The purpose of this study was to investigate the effect and its mechanism of mifepristone on the proliferation, apoptosis and DDP sensitivity of DDP-resistant human ovarian carcinoma cells, and to give experimental basis for treating refractory ovarian carcinoma with mifepristone.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1000-467X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
406-11
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pubmed:dateRevised |
2010-3-23
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pubmed:meshHeading |
pubmed-meshheading:15087028-Apoptosis,
pubmed-meshheading:15087028-Cell Cycle,
pubmed-meshheading:15087028-Cell Division,
pubmed-meshheading:15087028-Cell Line, Tumor,
pubmed-meshheading:15087028-Cisplatin,
pubmed-meshheading:15087028-Dose-Response Relationship, Drug,
pubmed-meshheading:15087028-Drug Resistance, Neoplasm,
pubmed-meshheading:15087028-Female,
pubmed-meshheading:15087028-Humans,
pubmed-meshheading:15087028-Mifepristone,
pubmed-meshheading:15087028-Ovarian Neoplasms
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pubmed:year |
2004
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pubmed:articleTitle |
[Effects of mifepristone on the proliferation, apoptosis, and cis-platinum (DDP) sensitivity of chemo-resistant human ovarian cancer cells].
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pubmed:affiliation |
Department of Obstetrics and Gynecology,The First People's Hospital of Foshan, Foshan, Guangdong, PR China. wgang@fsyyy.com
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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