|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2004-4-16
|
|
pubmed:abstractText |
Chronic metabolic acidosis leads to an increase in NHE3 activity that is mediated by endothelin-1 (ET-1) expression and activation of the proximal tubule endothelin B receptor. Chronic metabolic acidosis increases preproET-1 mRNA abundance in kidney cortex, but the cell responsible has not been identified.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0085-2538
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
65
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1320-6
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:15086471-Acidosis,
pubmed-meshheading:15086471-Animals,
pubmed-meshheading:15086471-Aorta,
pubmed-meshheading:15086471-Autocrine Communication,
pubmed-meshheading:15086471-Chronic Disease,
pubmed-meshheading:15086471-Endothelin-1,
pubmed-meshheading:15086471-Kidney Cortex,
pubmed-meshheading:15086471-Kidney Glomerulus,
pubmed-meshheading:15086471-Kidney Tubules, Proximal,
pubmed-meshheading:15086471-Male,
pubmed-meshheading:15086471-Myocardium,
pubmed-meshheading:15086471-RNA, Messenger,
pubmed-meshheading:15086471-Rats,
pubmed-meshheading:15086471-Rats, Sprague-Dawley,
pubmed-meshheading:15086471-Sodium-Hydrogen Antiporter
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3.
|
|
pubmed:affiliation |
Department of Internal Medicine and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
