Source:http://linkedlifedata.com/resource/pubmed/id/15083341
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| Predicate | Object |
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| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2004-4-14
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| pubmed:abstractText |
Because of problems with pacing devices, surgical procedures, and diaphragm fatigue in pacing therapy of the phrenic nerve, we performed simultaneous pacing of the diaphragm alone and of multiple respiratory muscles in dogs and evaluated the optimal tidal volume. After intravenously anesthetizing 20 dogs with an average weight of 11 kg, their tidal volume was measured with a spirometer to obtain control values. In the first 4 dogs, electrodes were sutured to the diaphragm and the optimal voltage, pulse width, and output to maximize tidal volume were determined. In the remaining 16 dogs, we stimulated individual canine respiratory muscles, i.e., the diaphragm, the rectus thoracis, and intercostal muscles 3-5 and simultaneously stimulated the diaphragm and the rectus thoracis; the diaphragm and intercostal muscles; the rectus thoracis and the intercostal muscles; or the diaphragm, rectus thoracis, and intercostal muscles. We compared a group in which a counterelectrode was positioned in each muscle group (group A) with a group in which no counterelectrode was used (group B). The best tidal volume was obtained at 10 V, 50 Hz, and a pulse width of 1.0 ms. All the respiratory muscle pacings yielded better tidal volumes in group B than in group A. The greatest tidal volume was obtained with the rectus thoracis and intercostal muscle combination, suggesting the possibility of being able to reduce diaphragm fatigue by alternate pacing of these muscles and the diaphragm.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:issn |
1434-7229
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
7
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
27-9
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| pubmed:meshHeading | |
| pubmed:year |
2004
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| pubmed:articleTitle |
Experimental evaluation of the optimal tidal volume for simultaneous pacing of the diaphragm and respiratory muscles.
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| pubmed:affiliation |
First Department of Surgery, Tokyo Women's Medical University, School of Medicine, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan. tadachi@chi.twmu.ac.jp
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| pubmed:publicationType |
Journal Article
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