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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-4-14
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pubmed:abstractText |
Blo t 11 is a high molecular weight allergen from Blomia tropicalis with significant immunoglobulin (Ig)E binding frequency. Native and recombinant Blo t 11 are susceptible to degradation and the isolation and expression of the allergen is problematic thus obtaining sufficient amounts of purified Blo t 11 for antibody production is limiting. DNA-based immunization is an attractive alternative strategy that bypasses antigen purification for antibody production.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Plant,
http://linkedlifedata.com/resource/pubmed/chemical/Blo t 11 allergen,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/Dust,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Immune Sera,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tropomyosin
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0105-4538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
539-47
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15080836-Allergens,
pubmed-meshheading:15080836-Amino Acid Sequence,
pubmed-meshheading:15080836-Animals,
pubmed-meshheading:15080836-Antibodies, Monoclonal,
pubmed-meshheading:15080836-Antibody Formation,
pubmed-meshheading:15080836-Antigens, Plant,
pubmed-meshheading:15080836-DNA,
pubmed-meshheading:15080836-Dust,
pubmed-meshheading:15080836-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15080836-Epitopes,
pubmed-meshheading:15080836-Female,
pubmed-meshheading:15080836-Humans,
pubmed-meshheading:15080836-Immune Sera,
pubmed-meshheading:15080836-Immunization,
pubmed-meshheading:15080836-Immunoglobulin E,
pubmed-meshheading:15080836-Mice,
pubmed-meshheading:15080836-Mice, Inbred BALB C,
pubmed-meshheading:15080836-Mites,
pubmed-meshheading:15080836-Molecular Sequence Data,
pubmed-meshheading:15080836-Recombinant Proteins,
pubmed-meshheading:15080836-Tropomyosin
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pubmed:year |
2004
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pubmed:articleTitle |
DNA immunization for the production of monoclonal antibodies to Blo t 11, a paramyosin homolog from Blomia tropicalis.
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pubmed:affiliation |
Department of Paediatrics, National University of Singapore, Singapore.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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