rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-4-12
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pubmed:abstractText |
In the era of postgenomic research, linkage- and association-based strategies are beginning to reveal novel complex disease genes. Using such an approach, a functional haplotype of the peptidylarginine deiminase 4 gene (PADI4) has recently been identified as a gene conferring susceptibility to rheumatoid arthritis (RA) in a Japanese population. In the present study, we investigated the association of single-nucleotide polymorphisms (SNPs) in the PADI4 gene with RA in a UK population.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1117-21
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15077293-Adult,
pubmed-meshheading:15077293-Arthritis, Rheumatoid,
pubmed-meshheading:15077293-Asian Continental Ancestry Group,
pubmed-meshheading:15077293-European Continental Ancestry Group,
pubmed-meshheading:15077293-Female,
pubmed-meshheading:15077293-Gene Frequency,
pubmed-meshheading:15077293-Genetic Predisposition to Disease,
pubmed-meshheading:15077293-Great Britain,
pubmed-meshheading:15077293-Haplotypes,
pubmed-meshheading:15077293-Humans,
pubmed-meshheading:15077293-Hydrolases,
pubmed-meshheading:15077293-Japan,
pubmed-meshheading:15077293-Male,
pubmed-meshheading:15077293-Middle Aged,
pubmed-meshheading:15077293-Polymorphism, Single Nucleotide
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pubmed:year |
2004
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pubmed:articleTitle |
A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population.
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pubmed:affiliation |
University of Manchester, Manchester, UK. ABarton@fs1.ser.man.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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