Linked Life Data

15077059

Source:http://linkedlifedata.com/resource/pubmed/id/15077059

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2004-4-12
pubmed:abstractText
Genistein, a naturally occurring isoflavonoid, displays antitumor, antimetastatic and antiangiogenic properties, described in various experimental in vitro and in vivo models. The results of several epidemiological studies suggest that soybean consumption may contribute to lower incidence of breast, colon, prostate, thyroid, and head and neck cancers. This protective effect of soy consumption is attributed, among others, to genistein. On the other hand, genistein may enhance the proliferation of some estrogen-positive human breast cancer cells in vivo and the growth of mammary gland and mammary cancer cells in athymic mice. In this paper, various aspects of the diverse biological activities of genistein and their potential clinical implications, especially in the treatment and prevention of cancer, are reviewed and discussed.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1732-2693
pubmed:author
pubmed:issnType
Electronic
pubmed:day
27
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
128-39
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Genistein: a soy isoflavone revealing a pleiotropic mechanism of action - clinical implications in the treatment and prevention of cancer].
pubmed:affiliation
Zak?ad Immunologii Nowotworów, Instytutu Immunologii i Terapii Do?wiadczalnej im. L. Hirszfelda, PAN we Wroc?awiu.
pubmed:publicationType
Journal Article, English Abstract, Review