Source:http://linkedlifedata.com/resource/pubmed/id/15076243
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-4-12
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pubmed:abstractText |
This study documented the HIV-1 subtype distribution in 2 Belgian hospitals and determined predictive demographics for non-B subtypes. Overall, subtype B was the most prevalent subtype in this population, followed by subtypes A and C. Several recombinants were detected, circulating recombinants as well as new ones. We found a rise in non-B subtypes from 0% in 1983 to 57% in 2001. The Cochran-Armitage trend test (P < 0.001) as well as the correlation analysis (R = 0.71, P = 0.0006) was highly significant. Recombinants were also increasing in this patient population from 0% in 1983 to 10% in 2001, with good support from the statistical analyses (trend test P < 0.001; correlation analysis R = 0.67, P = 0.0016). Heterosexual route of infection, black African race, African origin of the virus, and year of diagnosis were predictors for infection with non-B subtypes in multivariate analysis. This analysis indicates that the prevalence of non-B subtypes and recombinants in this patient population is high and increasing. Gathering demographic and sequence information from newly diagnosed patients could be useful to further follow the spread of non-B subtypes in Belgium and Europe, but subtyping based on sequence information still remains the most reliable method.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1525-4135
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pubmed:author |
pubmed-author:ClumeckNathanN,
pubmed-author:De WitStéphanieS,
pubmed-author:DerdelinckxIngeI,
pubmed-author:HermansPhilippeP,
pubmed-author:SchrootenYoeriY,
pubmed-author:SnoeckJokeJ,
pubmed-author:Van LaethemKristelK,
pubmed-author:Van WijngaerdenEricE,
pubmed-author:VandammeAnne-MiekeAM,
pubmed-author:van de VijverDavid A M CDA
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
279-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15076243-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:15076243-Adult,
pubmed-meshheading:15076243-Belgium,
pubmed-meshheading:15076243-Continental Population Groups,
pubmed-meshheading:15076243-Female,
pubmed-meshheading:15076243-Geography,
pubmed-meshheading:15076243-HIV Infections,
pubmed-meshheading:15076243-HIV-1,
pubmed-meshheading:15076243-Humans,
pubmed-meshheading:15076243-Male,
pubmed-meshheading:15076243-Sexual Behavior
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pubmed:year |
2004
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pubmed:articleTitle |
Rising prevalence of HIV-1 non-B subtypes in Belgium: 1983-2001.
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pubmed:affiliation |
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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