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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-4-12
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pubmed:abstractText |
The novel antihypertensive agent, omapatrilat, is both an inhibitor of neutral endopeptidase and angiotensin-converting enzyme. This study investigated the effects of omapatrilat in comparison with an angiotensin I-receptor antagonist/diuretic combination on blood pressure, endothelial function and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats (SHRSP).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Biphenyl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Carbachol,
http://linkedlifedata.com/resource/pubmed/chemical/Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrochlorothiazide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazepines,
http://linkedlifedata.com/resource/pubmed/chemical/irbesartan,
http://linkedlifedata.com/resource/pubmed/chemical/omapatrilat
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0263-6352
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-37
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15076191-Animals,
pubmed-meshheading:15076191-Antihypertensive Agents,
pubmed-meshheading:15076191-Biological Availability,
pubmed-meshheading:15076191-Biphenyl Compounds,
pubmed-meshheading:15076191-Blood Pressure,
pubmed-meshheading:15076191-Carbachol,
pubmed-meshheading:15076191-Cardiomegaly,
pubmed-meshheading:15076191-Carotid Arteries,
pubmed-meshheading:15076191-Drug Synergism,
pubmed-meshheading:15076191-Echocardiography,
pubmed-meshheading:15076191-Endothelium, Vascular,
pubmed-meshheading:15076191-Female,
pubmed-meshheading:15076191-Hormones,
pubmed-meshheading:15076191-Hydrochlorothiazide,
pubmed-meshheading:15076191-Hypertension,
pubmed-meshheading:15076191-Male,
pubmed-meshheading:15076191-Nitric Oxide,
pubmed-meshheading:15076191-Pyridines,
pubmed-meshheading:15076191-Rats,
pubmed-meshheading:15076191-Rats, Inbred SHR,
pubmed-meshheading:15076191-Sex Characteristics,
pubmed-meshheading:15076191-Stroke,
pubmed-meshheading:15076191-Systole,
pubmed-meshheading:15076191-Tetrazoles,
pubmed-meshheading:15076191-Thiazepines,
pubmed-meshheading:15076191-Vasodilation
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pubmed:year |
2004
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pubmed:articleTitle |
Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences.
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pubmed:affiliation |
BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, UK. dg74s@clinmed.gla.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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